SLC1A2 ELISA Kit for Human(Homo sapiens) | EIAab.comSLC1A2 ELISA Kit for Human(Homo sapiens)

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SLC1A2 (Gene name),

Excitatory amino acid transporter 2 (Protein name ), EAA2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SLC1A2(EAAT2;GLT1);

Protein name:

Excitatory amino acid transporter 2;

Alternative:

Sodium-dependent glutamate/aspartate transporter 2;Glutamate/aspartate transporter II;Solute carrier family 1 member 2;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotrimer. Interacts with JUB.

Function:

Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

574

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

574:

KVTLAANGKS | ADCSVEEEPW | KREK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P43004

MIM:

600300

Pfam:

PF00375

STRING:

9606.ENSP00000278379

String:

P43004

KEGG:

hsa:6506

UniGene:

Hs.502338

Uniprot:

P43004

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ELISA Kit for Human Excitatory amino acid transporter 2

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E15494r

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Manual:

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96T

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ELISA Kit for Human Excitatory amino acid transporter 2

Cat.:

E15494h

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96T

ELISA Kit for Human Excitatory amino acid transporter 2

Cat.:

E15494m

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96T

CLIA Kit for Human Excitatory amino acid transporter 2

Cat.:

U15494h

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MSDS:

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Packing:

96T

CLIA Kit for Human Excitatory amino acid transporter 2

Cat.:

U15494m

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MSDS:

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Packing:

96T

CLIA Kit for Human Excitatory amino acid transporter 2

Cat.:

U15494r

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96T

Polyclonal Antibody for Human Excitatory amino acid transporter 2

Cat.:

P15494Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Excitatory amino acid transporter 2

Cat.:

P15494Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Excitatory amino acid transporter 2

Cat.:

P15494Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Excitatory amino acid transporter 2

Protein for Human Excitatory amino acid transporter 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex."
Arriza J.L. , Fairman W.A. , Wendy A. , Wadiche J.I. , Murdoch G.H. , Kavanaugh M.P. , Amara S.G.
J. Neurosci.14:5559-5569(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain cortex.
2.

"Molecular cloning of human brain glutamate/aspartate transporter II."
Shashidharan P. , Wittenberg I. , Plaitakis A.
Biochim. Biophys. Acta1191:393-396(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Brain.
3.

"Cloning and characterization of a glutamate transporter cDNA from human brain and pancreas."
Manfras B.J. , Rudert W.A. , Trucco M. , Boehm B.O.
Biochim. Biophys. Acta1195:185-188(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Pancreas.
4.

"DL-threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters."
Shimamoto K. , Lebrun B. , Yasuda-Kamatani Y. , Sakaitani M. , Shigeri Y. , Yumoto N. , Nakajima T.
Mol. Pharmacol.53:195-201(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain.
5.

"Cloning and characterization of the 3'-untranslated region of the human excitatory amino acid transporter 2 transcript."
Kim S.Y. , Chao W. , Choi S.Y. , Volsky D.J.
J. Neurochem.86:1458-1467(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
6.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
7.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
10.

"A trimeric quaternary structure is conserved in bacterial and human glutamate transporters."
Gendreau S. , Voswinkel S. , Torres-Salazar D. , Lang N. , Heidtmann H. , Detro-Dassen S. , Schmalzing G. , Hidalgo P. , Fahlke C.
J. Biol. Chem.279:39505-39512(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: QUATERNARY STRUCTURE
11.

"Exon-skipping splice variants of excitatory amino acid transporter-2 (EAAT2) form heteromeric complexes with full-length EAAT2."
Gebhardt F.M. , Mitrovic A.D. , Gilbert D.F. , Vandenberg R.J. , Lynch J.W. , Dodd P.R.
J. Biol. Chem.285:31313-31324(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORM 3);SUBUNIT

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